A Cognitive Neuroscience-Informed Mobile App Intervention to Enhance Motivated Behavior and …
Introduction Schizophrenia is associated with significant psychosocial impairments, which lead to poor quality of life [,]. Recent data suggest that negative symptoms, and amotivation in particular, are the single most important factor affecting functional disability in schizophrenia [,]. Recent cognitive neuroscience research demonstrates that motivational deficits in schizophrenia are characterized by impairments in reward prediction, maintenance of rewarding experiences to guide future behavior, and a reduction in higher effort allocation to obtain rewarding experiences [-]. The likelihood to anticipate experiences to be less rewarding and more effortful leads to significant functional impairments. Yet, some aspects of reward processing for individuals with schizophrenia may be preserved, such the degree to which reward experiences are perceived as pleasurable in the moment. Findings suggest that individuals with schizophrenia demonstrate intact hedonic experiences, as…
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