Alejandro Carnicer-Lombarte

Interfacing with the peripheral nervous system using mechanically compliant prosthesis PhD Student Research Interests Neural interfaces allow the establishment of connections between the nervous system and external electronics, and hold great potential in both the clinic and basic research. The peripheral nervous system is a particularly attractive site to position an interface. Nerves are easy to access surgically and action potentials carried by them correlate well with activity at their target. Although many designs for peripheral nerve interfaces have been developed, they all face a major challenge upon chronic implantation. Materials used in implants are orders of magnitude stiffer than most tissues, which tags them as foreign. As a result, the body responds to interface implantation with inflammation and fibrosis – a foreign body reaction – damaging the nearby fragile…

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